Number of cytoplasmic proteins (if tetramer is average oligomerization state)

Value 250000 Unitless
Organism Bacteria Escherichia coli
Reference Goodsell DS. Inside a living cell. Trends Biochem Sci. 1991 Jun16(6):203-6. p.203 right column 1st paragraphPubMed ID1891800
Primary Source A list of primary sources is given in the reference
Method Assuming dry cell mass of 2.8×10^-13g (BNID 103904), 25% of total dry mass is cytoplasmic protein (BNID 100019, Measurement method), average polypeptide mass 40kDa (BNID 105861), one arrives at~1,050,000 cytoplasmic proteins/cell. Assuming oligomerization state of protein is ~4 (BNID 100020) one arrives at 250,000 proteins/cell.
Comments excluding ribosomal proteins. See BNID 100088
Entered by Ron Milo, Paul Jorgensen, Mike Springer
ID 100085