| Range |
8 - 9 residues
|
| Organism |
Mammals |
| Reference |
Kisselev AF, Akopian TN, Goldberg AL. Range of sizes of peptide products generated during degradation of different proteins by archaeal proteasomes. J Biol Chem. 1998 Jan 23 273(4):1982-9. p.1982 right column 3rd paragraph & p.1989 right colimn 2nd paragraphPubMed ID9442034
|
| Primary Source |
Goldberg AL, Gaczynska M, Grant E, Michalek M, Rock KL. Functions of the proteasome in antigen presentation. Cold Spring Harb Symp Quant Biol. 1995 60: 479-90.PubMed ID8824421
|
| Comments |
"In mammalian cells,
some of these peptides are utilized in antigen presentation,
possibly after further proteolytic processing to the final 8–9-
residue peptides presented on the cell surface (primary source)...Analogous studies of product size with eukaryotic proteasomes
are also of particular interest because of their role in generating
the 8–9-residue peptides used in MHC class 1 antigen
presentation (primary source)." Note-value of 8 - 10 residues given by PMID 11350924 p.2357 left column bottom paragraph |
| Entered by |
Uri M |
| ID |
109948 |