| Value |
13
Sec
Range: Table - link Sec
|
| Organism |
Mammals |
| Reference |
Peth A, Nathan JA, Goldberg AL. The ATP costs and time required to degrade ubiquitinated proteins by the 26 S proteasome. J Biol Chem. 2013 Oct 4 288(40):29215-22. doi: 10.1074/jbc.M113.482570 p.10 Table 1PubMed ID23965995
|
| Method |
"Initial experiments used 26S proteasomes gently
isolated from yeast (16) to determine whether they
hydrolyze ATP by a stochastic or a highly
cooperative manner, such as the cyclical, ordered
mechanism proposed recently in which nucleotides
bind and exchange in pairs (13)." |
| Comments |
See note beneath table. With folic acid added degradation time is 23 sec. |
| Entered by |
Uri M |
| ID |
109850 |