Typical mRNA halflife (determined by northern blotting or RNase protection)

Range 60 - 120 sec
Organism Bacteria Escherichia coli
Reference Mackie GA RNase E: at the interface of bacterial RNA processing and decay. Nat Rev Microbiol. 2013 Jan11(1):45-57. doi: 10.1038/nrmicro2930. p.49 right column 2nd paragraphPubMed ID23241849
Method "Northern blotting or RNase protection"
Comments "Thus, in E. coli, typical mRNA half-lives (determined by northern blotting or RNase protection) are 60–120 seconds, although a few mRNAs (for example, ompA) display half-lives of up to 15 minutes [BNID 111535]."
Entered by Uri M
ID 111534