| Primary Source |
[1] Kunst, F., Ogasawara, N., Moszer, I. & 148 other authors (1997). The complete genome sequence of the Gram-positive bacterium Bacillus subtilis . Nature 390 , 249–256 [2] Blattner, F. R., Plunkett, G., III, Bloch, C. A. & 14 other authors (1997). The complete genome sequence of Escherichia coli K-12. Science 277 , 1453–1461.PubMed ID9384377, 9278503
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| Comments |
"The sequencing of the regions surrounding replication origins of both B. subtilis (Ogasawara & Yoshikawa, 1992) and E. coli (Burland et al., 1993) showed that the genes are systematically coded in the leading strand. However, sequencing of the two complete genomes resulted in very different observations (Fig. 3) The frequency of leading strand genes is ~75 % in B. subtilis (primary source [1]), but only ~55 % in E. coli (primary source [2]). A first systematic survey of gene strand bias showed that genomes could have from 55 to 80 % of genes in the leading strand, although systematically more than 85 % of ribosomal proteins were coded in the leading strand of these genomes (McLean et al ., 1998)." Wikipedia:"T. tengcongensis...[was] reclassified as subspecies of Caldanaerobacter subterraneus." |