Table - link nm
||Erickson HP. Size and shape of protein molecules at the nanometer level determined by sedimentation, gel filtration, and electron microscopy. Biol Proced Online. 2009 May 15 11: 32-51. doi: 10.1007/s12575-009-9008-x. p.34 table 1PubMed ID19495910
||"Assuming this partial specific volume (v2=0.73 cm^3/g BNID 110540), [researchers] can
calculate the volume occupied by a protein of mass M in Dalton
Vnm^3=[(0.73cm^3/g)X(10^21nm^3/cm^3)/(6.023X10^23Da/g)] X M(Da)=1.212X10^-3nm^3/Da X M(Da).
The inverse relationship is also frequently useful: M (Da)=
825V (nm^3). What [researchers] really want is a physically intuitive parameter for the
size of the protein. If [they] assume the protein has the simplest
shape, a sphere, [they] can calculate its radius. [They] will refer to this
, because it is the minimal radius of a sphere that could
contain the given mass of protein Rmin=
(for M in Dalton, Rmin in nanometer)."
||"Some useful examples for proteins from 5,000 to 500,000 Da are
It is important to emphasize that this is the minimum radius
of a smooth sphere that could contain the given mass of protein.
Since proteins have an irregular surface, even ones that are approximately spherical will have an average radius larger than the