Ratio of mRNA nucleotides per ribosome on average

Value 154 nucleotides
Organism Budding yeast Saccharomyces cerevisiae
Reference Zenklusen D, Larson DR, Singer RH. Single-RNA counting reveals alternative modes of gene expression in yeast.Nat Struct Mol Biol. 2008 Dec15(12):1263-71.PubMed ID19011635
Method an in situ hybridization (FISH) approach that detects single mRNA molecules, mRNA abundance and transcriptional activity within single Saccharomyces cerevisiae cells was measured. See fig. 8a: Synthesis time was plotted against the length of the gene. The slope of the line gives (polymerase speed)^-1
Comments This value is termed 'ribosome density'. It is similar to that found by (Arava, 2003, pubmed 12660367), which was 1 ribosome per 156 nts
Entered by Uri M
ID 103026