Fraction of vesicles labelled by VGLUT2 [Vesicular glutamate transporter 2] antibodies

Range 23.3 %
Organism Rat Rattus norvegicus
Reference Takamori S et al., Molecular anatomy of a trafficking organelle. Cell. 2006 Nov 17 127(4):831-46. DOI: 10.1016/j.cell.2006.10.030 p.836 left column 2nd paragraphPubMed ID17110340
Method Immunogold labeling on purified vesicles
Comments P.836 left column 2nd paragraph: "[Investigators] also included two vesicular glutamate transporters, VGLUT1 and VGLUT2, in [their] analysis. These transporters display a differential localization in the brain and are known to reside on nonoverlapping vesicle subpopulations (Fremeau et al., 2001). To estimate their relative contribution, [they] performed immunogold labeling on purified vesicles. VGLUT1 antibodies and VGLUT2 antibodies labeled 66.8% and 23.3% of the vesicles, respectively."
Entered by Uri M
ID 102729