Average life span of an erythrocyte

Range ~120 days
Organism Human Homo sapiens
Reference Vander, A., J. Sherman, et al. (2001). Human physiology: the mechanisms of body function. Boston, McGraw-Hill higher education. p.377 left column 2nd paragraph
Comments "Because erythrocytes lack nuclei and organelles, they can neither reproduce themselves nor maintain their normal structure for very long. The average life span of an erythrocyte is approximately 120 days, which means that almost 1 percent of the body’s erythrocytes are destroyed and must be replaced every day. This amounts to 250 billion cells per day! Erythrocyte destruction normally occurs in the spleen and the liver." For ~120 days see PMID 20276177 p.627 2nd paragraph ("Callender, Powell, and Witts (8) using Ashby’s differential agglutination method (3) in Rh-positive men (9) concluded from a mathematical analysis of their data that red blood cells live for approximately 120 days.") See BNID 107875
Entered by Armindo Salvador
ID 101706