Distribution of cell number and mass for different cell types in the human body (for a 70 kg adult man)

Range Figure - link
Organism Human Homo sapiens
Reference Sender R, Fuchs S, Milo R. Revised Estimates for the Number of Human and Bacteria Cells in the Body. PLoS Biol. 2016 Aug 19 14(8):e1002533. doi: 10.1371/journal.pbio.1002533. P.9 figure 3PubMed ID27541692
Comments P.8 3rd paragraph to p.9 top paragraph: "Fig 3 compares the main tissues that contribute to the human body, in terms of cell number and masses. A striking outcome of this juxtaposition is the evident discordance between contributors to total cell mass and to cell number. The cell count is dominated by red blood cells (84%), among the smallest cell types in the human body with a volume of about 100 μm^3. In contrast, 75% of total cell mass is composed of two cell types, fat cells (adipocytes) and muscle cells (myocytes), both large cells (usually >10,000 μm^3 by volume) that constitute only a minute fraction (≈0.2%) of total cell number. At the other extreme, bacteria have a minor contribution in terms of mass, but a cell count comparable to all human cells combined, as discussed above. The mass balance accounts well for all expected body mass, giving support to [investigators’] analysis. The option of overlooking a collection of very small cells numerous enough to alter the total cell count is further discussed in the S1 Appendix." See note beneath figure
Entered by Uri M
ID 113005