Average width of planar Purkinje cell dendritic tree

Value 7 µm
Organism Mouse Mus musculus
Reference Li L et al., Visualizing the distribution of synapses from individual neurons in the mouse brain. PLoS One. 2010 Jul 9 5(7):e11503. doi: 10.1371/journal.pone.0011503. p.7 right column top paragraphPubMed ID20634890
Primary Source Mukamel EA, Nimmerjahn A, Schnitzer MJ (2009) Automated analysis of cellular signals from large-scale calcium imaging data. Neuron 63: 747–760.PubMed ID19778505
Method Primary source abstract:"[Investigators] used automated procedures to analyze data recorded by two-photon Ca(2+) imaging in the cerebellar vermis of awake behaving mice."
Comments p.6 left column bottom paragraph to right column top paragraph:"[Investigators’] finding [BNID 112026] implies that granule cells make denser connections in the molecular layer than previously thought. A recent study using calcium imaging suggests that the width of planar Purkinje cell dendritic tree is on average 7µm [primary source]. Given that each parallel fiber usually forms 1–2 synapses with a Purkinje cell [PMID 16759785], it is possible that a parallel fiber synapses with almost all Purkinje cells whose dendritic branches are within its reach."
Entered by Uri M
ID 112027