Distribution of Na+ in body

Range intracellular fluid ~10% extracellular fluid 50-60% bone 30-40% %
Organism vertebrates
Reference OS. Andersen, "Cellular Electrolyte Metabolism", in Encyclopedia of metalloproteins, eds. Robert H Kretsinger Vladimir N Uversky E A Permi?a?kov, Springer 2013 pp.580-587 p.584 left column 2nd paragraph
Comments "Considering the distribution of the body water between the intracellular and extracellular compartments and the chemical composition of the compartments, one can deduce that most of the body’s Na+ is in the extracellular fluid, whereas most of the K+ is in the intracellular fluid. There are ~60 mmoles of Na+ per kg body mass: ~10% in the intracellular fluid. 50-60% in the extracellular fluid. and the rest in bone...Even small shifts of K+ from the intracellular to the extracellular compartment thus may lead to large changes in the extracellular [K+] concentration, [K+]e, and vice versa for Na+."
Entered by Uri M
ID 110756