Fidelity of HIV-1 and AMV reverse transcriptases and cellular DNA polymerases in a base subsitution reversion assay

Range Table - link
Organism Various
Reference Roberts JD, Bebenek K, Kunkel TA. The accuracy of reverse transcriptase from HIV-1. Science. 1988 Nov 25 242(4882):1171-3. p.1172 table 1PubMed ID2460925
Method See note above table
Comments "HIV-1 RT generated revertants at a frequency of 100x10^-6 (Table 1). This is more than 50 times above the spontaneous background reversion frequency of uncopied DNA, showing that errors are indeed the result of DNA polymerization in vitro." AMV=avian myeloblastosis virus
Entered by Uri M
ID 110132