Thickness of cerebral cortex

Range ~2.5 (1 - 4.5) mm
Organism Human Homo sapiens
Reference Fischl B, Dale AM. Measuring the thickness of the human cerebral cortex from magnetic resonance images. Proc Natl Acad Sci U S A. 2000 Sep 26 97(20):11050-5. p.11050 left column 2nd paragraphPubMed ID10984517
Primary Source 1. Zilles, K. (1990) in The Human Nervous System, ed. Paxinos, G. (Academic, San Diego), pp. 757–802. 2. von Economo, C. (1929) The Cytoarchitectonics of the Human Cerebral Cortex (Oxford Univ. Press, London). 3. Brodmann, K. (1909) Vergleichende Lokalisationslehre der Großhirnrinde in ihren Prinzipien dargestellt auf Grund des Zellenbaues (Barth, Leipzig, Germany).
Comments "The human cerebral cortex is a highly folded sheet of neurons the thickness of which varies between 1 and 4.5 mm, with an overall average of approximately 2.5 mm (primary sources). Regional variations in the cortical thickness can be quite large. For example, Brodmann’s area 3 on the posterior bank of the central sulcus is among the thinnest of cortical regions, with an average thickness of less than 2 mm, whereas Brodmann’s area 4 on the anterior bank is one of the thickest regions, frequently exceeding 4 mm. Interestingly, the distribution of the thickness is not uniform by layer, nor is the variation in the thickness of the cortical layers proportional to the variation in the total thickness."
Entered by Uri M
ID 110098