| Range |
~137,000 ATP/vesicle
|
| Organism |
Eukaryotes |
| Reference |
Attwell D, Laughlin SB. An energy budget for signaling in the grey matter of the brain. J Cereb Blood Flow Metab. 2001 Oct21(10):1133-45. p.1138 left column bottom paragraphPubMed ID11598490
|
| Method |
"Calculated in Materials
and Methods from the number of channels activated per
vesicle and their conductance, open time, and reversal
potential." |
| Comments |
"...the major energy expenditure is on reversing the
ion movements evoked by glutamate’s actions on postsynaptic
NMDA and non-NMDA ionotropic receptors,
which together require hydrolysis of approximately
137,000 ATP molecules/vesicle." |
| Entered by |
Uri M |
| ID |
108665 |