Mean duration of G1 cell phase in HeLa cells

Range ~400 min
Organism Mammalian tissue culture cell
Reference Hahn AT, Jones JT, Meyer T. Quantitative analysis of cell cycle phase durations and PC12 differentiation using fluorescent biosensors. Cell Cycle. 2009 Apr 1 8(7):1044-52. p.1047 fig.2BPubMed ID19270522
Method "Live-cell fluorescent biosensors and time-lapse microscopy allows the collection of temporal information about real time cell cycle progression and arrest." Value estimated visually from figure 2B
Comments "Though the average duration of a completed G1 phase does not differ significantly among the three cell types, when comparing the time spent in G1 phase for single NIH3T3, NCI-H292 and HeLa cells, [investigators] found a marked bimodal behavior that was unique to NIH3T3 fibroblast cells. Figure 2B shows histograms of the time individual cells of the three cell types spent in G1 phase."
Entered by Uri M
ID 108483