| Range |
2 to 7 %
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Nath K, Koch AL. Protein degradation in Escherichia coli. I. Measurement of rapidly and slowly decaying components. J Biol Chem. 1970 Jun 10 245(11):2889-900. p.2889 left column 2nd paragraphPubMed ID4912536
|
| Method |
"The rate of degradation of intracellular radioactive protein of bacterial cells supported by a membrane filter has been measured directly from the appearance of radioactivity in the carrier-containing perfusate. For this purpose a perfusion apparatus has been constructed from a microsyringe filter holder." |
| Comments |
"Only
a
limited
portion
of
the
cellular
protein
is
subject
to
rapid
degradation.
It decays with a half-life of approximately
1 hour and constitutes 2 to 7% of the total cellular
protein of cells growing in glucose minimal medium under
various nutritional conditions (including growth and starvation). The proportion of the total protein synthesis which is directed to the synthesis of this rapidly degrading protein component increases with decreasing growth rate." |
| Entered by |
Uri M |
| ID |
108404 |