Percentage of newly synthesized proteins that are degraded by proteasome within minutes of synthesis

Range ≤30 %
Organism Eukaryotes
Reference Goldberg AL. Protein degradation and protection against misfolded or damaged proteins. Nature. 2003 Dec 18 426(6968):895-9. p.896 left column 4th paragraphPubMed ID14685250
Primary Source Schubert U, Antón LC, Gibbs J, Norbury CC, Yewdell JW, Bennink JR. Rapid degradation of a large fraction of newly synthesized proteins by proteasomes. Nature. 2000 Apr 13 404(6779):770-4.PubMed ID10783891
Comments As many as 30% of newly synthesized proteins in eukaryotes might undergo degradation within minutes of synthesis (primary source). See BNID 113356
Entered by Uri M
ID 108154