mRNA lifetimes of several transcripts

Range 0.9 to 2.8 Table - link Min
Organism Bacteria Escherichia coli
Reference So LH, Ghosh A, Zong C, Sepúlveda LA, Segev R, Golding I. General properties of transcriptional time series in Escherichia coli. Nat Genet. 2011 Jun43(6):554-60 Supplementary table S5PubMed ID21532574
Primary Source Ref AND Ptashne, M. A genetic switch : phage lambda revisited, xiv, 154 p. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y., 2004).
Method smFISH (single molecule Fluorescence in situ hybridization) and qPCR
Comments As expected, different transcripts exhibited different degradation rates, with more than a 3-fold range of mRNA lifetimes.
Entered by Uri M
ID 107666