Turnover rate of Malonyl-coenzyme A reductase

Value 28 1/sec/subunit
Organism Bacteria Escherichia coli
Reference Alber B, Olinger M, Rieder A, Kockelkorn D, Jobst B, Hügler M, Fuchs G. Malonyl-coenzyme A reductase in the modified 3-hydroxypropionate cycle for autotrophic carbon fixation in archaeal Metallosphaera and Sulfolobus spp. J Bacteriol. 2006 Dec188(24):8551-9 p. 8556 left column 2nd paragraphPubMed ID17041055
Method Heterologous expression of the malonyl-CoA reductase (mcr) gene from S. tokodaii and production of the protein in E. coli.
Comments The specific activity of malonyl-CoA reductase at 65°C was 44 µmol/mg/min (Table 1, p. 8553), corresponding to a turnover rate of 28 s^-1 per subunit. (molecular mass of a subunit is 39kDa)
Entered by Uri M
ID 105607