Time of apoptosis in primary liver cell

Value 3 Hours
Organism Human Homo sapiens
Reference Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK. Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature. 2009 May 21 459(7245):428-32PubMed ID19363473
Method 3 hours is the apoptotic time with greatest probability of cells treated with 50 ng/ml TRAIL + cycloheximide (bottom panel of supp. fig. 1) and imaged by brightfield microscopy every 10 min for 25.5 h. One hundred cells were analysed for each distribution. Death time was scored as the first frame of apoptotic morphology.
Entered by Uri M
ID 104875