Titre and rate constant (kcat/Km) of superoxide dismutases (SODs) and steady state O2− (superoxide) concentration

Range SOD titre 20μM: SOD kcat/Km 10^9M^−1×s^−1: O2− steady-state concentration ~0.2nM
Organism Bacteria Escherichia coli
Reference Imlay JA. The molecular mechanisms and physiological consequences of oxidative stress: lessons from a model bacterium. Nat Rev Microbiol. 2013 Jul11(7):443-54. doi: 10.1038/nrmicro3032. p.446 Box 2 bottom paragraphPubMed ID23712352
Comments P.446 Box 2 bottom paragraph: "The rate of endogenous O2− formation is probably slightly lower [than H2O2](~5μM/s)[BNID 112943]. The titre (20 μM) and rate constant (10^9M^−1×s^−1) of superoxide dismutases (SODs) mean that steady-state O2− levels are ~0.2 nM, or fewer than one molecule per cell."
Entered by jpbrody
ID 112948