Increase in plasma volume (measured between late pregnancy & 8 days post-partum)

Range according to Lowenstein -4% to +77%: according to Lund +14% to +121% %
Organism Human Homo sapiens
Reference Hytten F. Blood volume changes in normal pregnancy. Clin Haematol. 1985 Oct14(3):601-12. p.603 3rd paragraphPubMed ID4075604
Primary Source Lowenstein L, Pick CA, Philpott NW. Correlation of blood loss with blood volume and other hematological studies before, during and after childbirth. Am J Obstet Gynecol. 1950 Dec60(6):1206-16. AND Lund CJ. Studies on the iron deficiency anemia of pregnancy including plasma volume, total hemoglobin, erythrocyte protoporphyrin in treated and untreated normal and anemic patients. Am J Obstet Gynecol. 1951 Nov62(5):947-63.PubMed ID14789883, 14885278
Comments P.603 3rd paragraph:"Attempts to measure blood and plasma volume began 70 years ago (as of 1985, Miller et al., 1915), but the modern era of measurement using Evans blue dye began with the work of Thomson et al (1938). Many studies have followed and they were listed in detail by Hytten and Leitch (1971). Little would be gained by repeating that compilation it is enough to say that most of the studies were seriously flawed and led to confusion about both the extent and the individual variation of the change. As examples, [primary source] Lowenstein et al (1950) who studied 35 ‘unselected’ women ranging in parity from nought to seven and in age from 17 to 42, found an increase in plasma volume (measured between late pregnancy and eight days post-partum) ranging from -4% to +77%. And [primary source] Lund (1951) whose subjects were mostly black women ‘exclusively from the low-income groups’ found a range from +14% to +121%."
Entered by Uri M
ID 112356