| Range |
Figure - link
|
| Organism |
Rat Rattus norvegicus |
| Reference |
Sudhof TC. The synaptic vesicle cycle. Annu Rev Neurosci. 2004 27: 509-47. p.513 figure 2PubMed ID15217342
|
| Primary Source |
Meinrenken CJ, Borst JG, Sakmann B. 2003. Local routes revisited: the space and time dependence of the Ca2+ signal for phasic transmitter release at the rat calyx of Held. J. Physiol. 547: 665–89PubMed ID12562955
|
| Comments |
"The size of the calyx allows direct electrophysiological recordings from a terminal,
making it possible to monitor pre- and postsynaptic events simultaneously
(Figure 2). Major advances in [researchers'] understanding of neurotransmitter release were
made in the calyx of Held by relating the precise concentration and dynamics of
Ca2+ to synaptic vesicle exocytosis (reviewed in Schneggenburger et al. 2002,
and in primary source). When an action potential invades the calyx terminal, the
Ca2+ current begins at the peak of the action potential and ends before the calyx
terminal is fully repolarized (Figure 2: Helmchen et al. 1997)." |
| Entered by |
Uri M |
| ID |
111281 |