Permeability coefficients (pm) through egg PC-decane bilayers and partition coefficients (Kp) into hexadecane (hex), olive oil (oil), octanol (oct) and ether (eth)

Range Table - link unitless
Organism Generic
Reference Walter A, Gutknecht J. Permeability of small nonelectrolytes through lipid bilayer membranes. J Membr Biol. 1986 90(3):207-17. p.211 table 1PubMed ID3735402
Primary Source See pointers to refs beneath table
Method "Diffusion of small nonelectrolytes through planar lipid bilayer membranes (egg phosphatidylcholine-decane) was examined by correlating [least square regression analysis] the permeability coefficients of 22 solutes with their partition coefficients between water and four organic solvents."
Comments "If solute permeability through a lipid bilayer is governed by the same forces that determine its partitioning into nonaqueous solvents, then pm and Kp should correlate. Figure 2 shows the relationships between membrane permeability and partition coefficients into (a) hexadecane, (b) olive oil, (c) octanol, and (d) ether. The exact values of pm [membrane permeability] and Kp [partition coefficient] are given in Table 1."
Entered by Uri M
ID 110816