Metabolite concentrations in iBMK cells

Range Table - link nmole/μl cells
Organism Mammalian tissue culture cell
Reference Fan J, Kamphorst JJ, Mathew R, Chung MK, White E, Shlomi T, Rabinowitz JD. Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia. Mol Syst Biol. 2013 Dec 3 9: 712. doi: 10.1038/msb.2013.65. Supplementary information p.10 table 4PubMed ID24301801
Comments "As a further validation of the inferred fluxes, [researchers] measured the kinetic labeling of intracellular metabolites (for 72 h) as well as their absolute concentrations (Supplementary Table 4). The fluxes obtained solely by fitting the steady-state data resulted also in good agreement with the experimentally observed kinetic labeling patterns (Methods Supplementary Figures 1–4)." iBMK=Immortalized baby mouse kidney epithelial cells
Entered by Uri M
ID 110688