Ratio between volume of major Organelles to that of the Cell (O:C)

Range 0.18-0.21 unitless
Organism Yeast
Reference Uchida M, Sun Y, McDermott G, Knoechel C, Le Gros MA, Parkinson D, Drubin DG, Larabell CA. Quantitative analysis of yeast internal architecture using soft X-ray tomography. Yeast. 2011 Mar28(3):227-36. doi: 10.1002/yea.1834. link p.234 left column top paragraph PubMed ID21360734
Method Abstract: "[Researchers] used soft X-ray tomography (SXT)-a high-resolution, quantitative imaging technique-to measure cell size and organelle volumes in yeasts."
Comments P.233 right column bottom paragraph to p.234 left column top paragraph: "This work demonstrates that both haploid and diploid cells of S. cerevisiae maintain a constant ratio of total major organelle volume to cell volume throughout the cell cycle. To find out whether this correlation was influenced by morphology, species or mutation, [researchers] characterized C. albicans, Sz. pombe and a S. cerevisiae mutant. Surprisingly, similar O: C ratios (i.e. 0.18–0.21) were observed in C. albicans that exhibited three different phenotypes (i.e. yeast-like, germ tubes and hyphae), Sz. pombe cells at the different stages of cell cycle, and cofilin mutant cells (coff1-22) (data not shown)."
Entered by Uri M
ID 110471