Number of different assembly factors (proteins) that participate in the formation of ribosomes in addition to ribosomal proteins

Range ~200 different factors
Organism Budding yeast Saccharomyces cerevisiae
Reference Woolford JL Jr, Baserga SJ. Ribosome biogenesis in the yeast Saccharomyces cerevisiae. Genetics. 2013 Nov195(3):643-81. doi: 10.1534/genetics.113.153197. p.652 left column bottom paragraphPubMed ID24190922
Comments "In addition to r-proteins, ~200 different assembly factors participate in the formation of ribosomes in yeast (Table 3 and Table 4). Most of these proteins are essential and conserved throughout eukaryotes, and all are present in assembling ribosomes. Yeast ribosome assembly factors were first discovered by classic or molecular genetic approaches (Fabian and Hopper 1987 Sachs and Davis 1990 Shuai and Warner 1991 Tollervey et al. 1991 Girard et al. 1992 Lee et al. 1992 Ripmaster et al. 1992 Jansen et al. 1993 Schmitt and Clayton 1993 Berges et al. 1994 Chu et al. 1994 Sun and Woolford 1994)." See BNID 112255
Entered by Uri M
ID 110025