Usual length of signal peptide

Range 15 - 30 amino acids
Organism Bacteria Escherichia coli
Reference Maurizi MR. Proteases and protein degradation in Escherichia coli. Experientia. 1992 Feb 15 48(2):178-201. p.183 left column 2nd paragraphPubMed ID1740190
Primary Source 105 Michaelis, S., and Beckwith, J., Mechanism of incorporation of cell envelope proteins in Escherichia coli. A. Rev. Microbiol. 36 (1982) 435-465. & 119 Oliver, D., Protein secretion in Eseheriehia eoli. A. Rev. Microbiol. 39 (1985) 615-648.PubMed ID6756294, 3904614
Comments "...the signal peptides are usually between 15 and 30 amino acids long (approximately 10% of the length of the precursor (primary source 105)) and membrane and periplasmic proteins constitute 10-15% of the protein mass of the cell (primary source 119), degradation of signal peptides amounts to turnover of perhaps 1% of the total cellular protein per generation, a significant but minor fraction of the rapidly degraded pool of polypeptides."
Entered by Uri M
ID 109923