Ratio between membrane thickness and radius of intracellular vesicle

Value 0.1 unitless
Organism Generic
Reference Graham TR, Kozlov MM. Interplay of proteins and lipids in generating membrane curvature. Curr Opin Cell Biol. 2010 Aug22(4):430-6. p.430 right column 1st paragraphPubMed ID20605711
Comments Curvature is considered to be small if the radii R1 and R2 (these are the radii of 2 perpendicular arcs that describe a membrane fragment) are much larger than the membrane thickness, h˜4 nm. An example is plasma membrane for which h/R˜10^-4 or less. By contrast, vesicular and tubular intracellular transport intermediates have h/R˜10^-1 so that their curvatures are considered to be large.
Entered by Uri M
ID 105555