Diffusion coefficient of Promyelocytic leukemia (PML) bodies in chromatin of HeLa cell

Value 120 µm^2/sec Range: ±31 µm^2/sec
Organism Human Homo sapiens
Reference Görisch SM, Wachsmuth M, Ittrich C, Bacher CP, Rippe K, Lichter P. Nuclear body movement is determined by chromatin accessibility and dynamics. Proc Natl Acad Sci U S A. 2004 Sep 7,101(36):13221-6.PubMed ID15331777
Method Fixation and Indirect Immunofluorescence. Confocal Laser Scanning and Correlative Electron Microscopy. Image Processing and Movement Analysis.
Comments Promyelocytic leukemia (PML) and Cajal bodies are mobile subnuclear organelles, which are involved in activities like RNA processing, transcriptional regulation, and antiviral defense.
Entered by Uri M
ID 104266