Early estimates of average lifespan of taste bud cells

Range 8 - 12 days
Organism Rodent
Reference Perea-Martinez I, Nagai T, Chaudhari N. Functional cell types in taste buds have distinct longevities. PLoS One. 2013 8(1):e53399. doi: 10.1371/journal.pone.0053399. abstract & p.1 right column bottom paragraphPubMed ID23320081
Primary Source Beidler LM, Smallman RL (1965) Renewal of cells within taste buds. J Cell Biol 27: 263–272. doi: 10.1083/jcb.27.2.263 & Conger AD, Wells MA (1969) Radiation and aging effect on taste structure and function. Radiat Res 37: 31–49. doi: 10.2307/3572749PubMed ID5884625, 5762923
Method P.1 right column 2nd paragraph:"Electron microscopic studies found that 3H-thymidine is first incorporated into basal epithelial cells outside taste bud boundaries and only appears within taste buds with the passage of time [primary sources]."
Comments P.1 right column bottom paragraph: "Early estimates using 3H-thymidine suggested that the average lifespan of taste bud cells in rodents is 8–12 days [primary sources]."
Entered by Uri M
ID 112167