Enterocyte volume

Range ~1,400 µm^3
Organism Human Homo sapiens
Reference Wisniewski JR, Ostasiewicz P, Dus K, Zielinska DF, Gnad F, Mann M. Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma. Mol Syst Biol. 2012 8: 611. doi: 10.1038/msb.2012.44. p.8 right column 2nd paragraphPubMed ID22968445
Primary Source Buschmann RJ, Manke DJ (1981) Morphometric analysis of the membranes and organelles of small intestinal enterocytes. I. Fasted Hamster. J Ultrastruct Res 76: 1–14 & MacLeod et al., (1991) Corticostatic peptides cause nifedipine-sensitive volume reduction in jejunal villus enterocytes. Proc Natl Acad Sci USA 88: 552–556 & Crowe PT, MarshMN(1993) Morphometric analysis of small intestinal mucosa. IV. Determining cell volumes. Virchows Arch A Pathol Anat Histopathol 422: 459–466PubMed ID7277572, 1703302, 8333150
Comments "To calculate copy numbers of proteins in the enterocytes, [researchers] assumed the volume of these cells to be about 1400µm^3 (primary sources) and the protein content of mammalian cells to be about 20% (BNID 111217)."
Entered by Uri M
ID 111216