||Bacteria Escherichia coli
||Blank LM, Ebert BE, Bühler B, Schmid A. Metabolic capacity estimation of Escherichia coli as a platform for redox biocatalysis: constraint-based modeling and experimental verification. Biotechnol Bioeng. 2008 Aug 15 100(6):1050-65. doi: 10.1002/bit.21837. p.1055 right column top paragraphPubMed ID18553399
||"In order to define maximal net NADH formation rates in
E. coli, which can serve as target values for redox cofactordependent
biocatalysis, [researchers] investigated the capability of
the E. coli metabolic network to regenerate the reduced
cofactor NADH during glucose catabolism by FBA using
a stoichiometric model of central carbon metabolism."
highest glucose uptake rate still allowing the maximal
NADH yield on glucose (2.4mmol/(gCDW?h) for E. coli)
can be considered as optimal and results in a theoretical
NADH formation rate of 22mmol/(gCDW?h)."