Statistical analysis of anticodon-dependent motifs of animal genomes

Range Table - link
Organism Eukaryotes
Reference Zhang G, Lukoszek R, Mueller-Roeber B, Ignatova Z. Different sequence signatures in the upstream regions of plant and animal tRNA genes shape distinct modes of regulation. Nucleic Acids Res. 2011 Apr39(8):3331-9. doi: 10.1093/nar/gkq1257. p.3336 table 1PubMed ID21138970
Method "Taking advantage of the large number of sequenced and annotated genomes, [researchers] have undertaken a systematic analysis of the upstream promoter regions of tRNA genes in several multicellular eukaryotic genomes...Using deep-sequencing data of the transcriptome of 16 human tissues, [researchers] identified multiple splicing variants of Bdp1 and Brf1 with a tissue-specific expression pattern."
Comments "...this search extracted anticodon-dependent motifs in the upstream segments of the majority of the tRNA families (Figure 2 and Supplementary Figure S4) in all tested animal genomes (Table 1 and Supplementary Table S1) however, no such dependence was observed for any of the plant genomes."
Entered by Uri M
ID 109633