Number of new cells generated in the adult rat dentate gyrus each day

Value 9000 Cells/day
Organism Rat Rattus norvegicus
Reference Cameron HA, McKay RD. Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J Comp Neurol. 2001 Jul 9 435(4):406-17. p.415 left column, bottom paragraphPubMed ID11406822
Method 5-bromo-2'-deoxyuridine (BrdU) immunohistochemistry. Calculation made by determining the length of the cell cycle for dividing cells and the total number of dividing cells
Comments This number is 18% of the estimated rate of 50,000 new cells per day generated at the peak of granule cell proliferation (Schlessinger et al., 1975 PMID 1112911)
Entered by Uri M
ID 106090