Length of fibroblast growth factor (FGF) and fibroblast growth factor receptor (FGFR)

Range FGF ~150-300: FGFR 800 Amino acids
Organism Human Homo sapiens
Reference Itoh N, Ornitz DM. Evolution of the Fgf and Fgfr gene families. Trends Genet. 2004 Nov20(11):563-9. p.563 right column top sentence and p.567 left column top sentence doi:10.1016/j.tig.2004.08.007PubMed ID15475116
Comments Human FGFs, which comprise ~150–300 amino acids, have a conserved ~120-amino acid residue core, with ~30–60% amino acid identity. The overall amino-acid identity among human FGFRs is 56–71%
Entered by Uri M
ID 105847