Time of a single RNA transcription

Value 1.2 min Range: 0.75-1.67 min
Organism Poliovirus
Reference Regoes RR, Crotty S, Antia R, Tanaka MM. Optimal replication of poliovirus within cells. Am Nat. 2005 Mar165(3):364-73. Table 1 Table - link PubMed ID15729666
Primary Source 1) Baltimore, D. 1969. The replication of picornaviruses. Pages 101–176 in H. B. Levy, ed. The biochemistry of viruses. Dekker, New York. (2) Arnold JJ, Cameron CE. Poliovirus RNA-dependent RNA polymerase (3D(pol)). Assembly of stable, elongation-competent complexes by using a symmetrical primer-template substrate (sym/sub). J Biol Chem. 2000 Feb 25 275(8):5329-36.PubMed ID(2) 10681506
Method Ref-Authors construct a mathematical model of the within-cell replication of poliovirus. Primary source (2)- Study of kinetics and mechanism of RNA dependent RNA pol by employing a short, symmetrical, heteropolymeric RNA primer-template.
Entered by Uri M
ID 105206