Histo Compatabilility 10- molecule half life

Value 7 Hours
Organism Mammals
Reference Carreno BM, Hansen TH. Exogenous peptide ligand influences the expression and half-life of free HLA class I heavy chains ubiquitously detected at the cell surface. Eur J Immunol. 1994 Jun24 (6):1285-92.PubMed ID8206088
Method Flow cytometry, Peptide labeling and binding, Immunoprecipitation pulse/chase experiments,
Comments HLA-B27 molecules (W6/32+) expressed on Hmy. C1R cells display a t1/2 > 7 h and peptide ligands have minimal effect on their cell surface turnover or expression
Entered by Uri M
ID 104755