Displacement of ferrous ion out of heme plane in deoxygenated state of hemoglobin

Value 0.4 Angstrom
Organism Human Homo sapiens
Reference Wood BR, McNaughton D. Micro-Raman characterization of high- and low-spin heme moieties within single living erythrocytes. Biopolymers. 2002 67(4-5):259-62.PubMed ID12012442
Primary Source Fermi G, Perutz MF, Shaanan B, Fourme R. The crystal structure of human deoxyhaemoglobin at 1.74 A resolution. J Mol Biol. 1984 May 15175(2):159-74PubMed ID6726807
Method The structure of human deoxyhaemoglobin was refined at 1.74 A resolution using data collected on film at room temperature from a synchrotron X-ray source.
Comments The distance of the iron from the mean plane of N(porphyrin) is 0.40(5) A and 0.36(5) A, respectively, at the alpha and beta haems, in contrast to the corresponding distance of +0.12(8) A and -0.11(8) A in oxyhaemoglobin ( Shaanan , 1983). Figures in parentheses are standard deviations of last digit.
Entered by Uri M
ID 104201