External concentration of alpha mating factor required for half maximal induction of agglutination

Value 0.1 nM
Organism Budding yeast Saccharomyces cerevisiae
Reference Moore SA. Comparison of dose-response curves for alpha factor-induced cell division arrest, agglutination, and projection formation of yeast cells. Implication for the mechanism of alpha factor action. J Biol Chem. 1983 Nov 25258(22):13849-56.PubMed ID6358212
Method yeast MATa cells respond to alpha pheromone by undergoing several inducible responses: the arrest of cell division, the production of a cell surface agglutinin, and the formation of one or more projections on the cell surface commonly termed the "shmoo" morphology. Dose-response curves were determined for each of these inducible responses as a function of alpha factor concentration.
Comments This value is nearly the same as that at which cells exhibit a half-maximal response for cell division arrest (0.25 nM, bion 103615)
Entered by Uri M
ID 103616