Intramembrane cross-sectional area of bacteriorhodopsin

Value 690 Å^2
Organism Unspecified
Reference Marsh D. Lateral pressure profile, spontaneous curvature frustration, and the incorporation and conformation of proteins in membranes. Biophys J. 2007 Dec 1 93(11):3884-99PubMed ID17704167
Primary Source Henderson R, Baldwin JM, Ceska TA, Zemlin F, Beckmann E, Downing KH. Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy.J Mol Biol. 1990 Jun 20 213(4):899-929.PubMed ID2359127
Method The light-driven proton pump bacteriorhodopsin occurs naturally as two-dimensional crystals. A three-dimensional density map of the structure, at near-atomic resolution, has been obtained by studying the crystals using electron cryo-microscopy to obtain electron diffraction patterns and high-resolution micrographs.
Comments the intramembrane cross-sectional dimensions (~38 Å × 23 Å ) are less than those of rhodopsin, corresponding to a cross-sectional area of AP ~ 690 Å^2
Entered by Uri M
ID 103606