Table - link
||Nowak MA, Evolutionary dynamics, The Belknap press of Harvard University press, 2006 p.40 table 3.1
||Drake JW, A constant rate of spontaneous mutation in DNA-based microbes.Proc Natl Acad Sci U S A. 1991 Aug 15 88(16):7160-4 AND Drake JW. Rates of spontaneous mutation among RNA viruses. Proc Natl Acad Sci U S A. 1993 May 1 90(9):4171-5 AND Drake JW, Charlesworth B, Charlesworth D, Crow JF. Rates of spontaneous mutation. Genetics. 1998 Apr148(4):1667-86.PubMed ID1831267, 8387212, 9560386
||2nd primary source Drake 1993: Poliovirus-"A?C was measured at one
site in the replicase gene [ref 11]." flu A-"an average of 849 bases was sequenced in each of 108 clonal copies of a gene encoding a nonstructural protein [ref 19]." VSV-"G?A frequencies were measured at two sites under conditions where phenotypic mixing and selection were negligible [ref 16]." mulv-Moloney murine leukemia virus-"using a MulV vector, the reversion of an amber mutation was measured in a selectively neutral neo insert in one provirus to provirus cycle [ref 22]."
||"In other words, the genomic mutation rate, uL, has to be less than one. In fact, this condition holds for most living organisms for which mutation rates have been measured (Table 3.1). For eukaryotes, the genome length L in this context should actually be defined as the total number of bases in the coding and regulatory regions of the DNA." See note beneath table