Fraction of white matter of central nervous system (CNS) that is myelin on a dry weight basis

Range 50 - 60 %
Organism Mammals
Reference Hildebrand C, Remahl S, Persson H, Bjartmar C. Myelinated nerve fibres in the CNS. Prog Neurobiol. 1993 Mar40(3):319-84 p.324 left column bottom paragraphPubMed ID8441812
Primary Source Norton WT, Autilio LA. The lipid composition of purified bovine brain myelin. J Neurochem. 1966 Apr13(4):213-22PubMed ID5937889
Comments P.323 right column bottom paragraph: "The mammalian CNS is composed of grey and white matter. Neuronal somata, glial cells and neuropil are major grey matter constituents. White matter consists primarily of axons and glial cells. Myelin, the fatty white coating that surrounds most CNS axons, was discovered and named more than a century ago (Virchow, 1854). Large amounts of myelin are present in the white matter (50-60% on a dry weight basis, primary source), and this component accounts for the characteristic whiteness of the tissue." Primary source studied cow
Entered by Uri M
ID 114484