Concentration of proteins in liver mitochondrial matrix

Range ~500 g/L
Organism Rat Rattus norvegicus
Reference Shahid S et al., Size-dependent studies of macromolecular crowding on the thermodynamic stability, structure and functional activity of proteins: in vitro and in silico approaches. Biochim Biophys Acta. 2017 Feb1861(2):178-197. doi: 10.1016/j.bbagen.2016.11.014 p.179 left column bottom paragraphPubMed ID27842220
Primary Source [20] P.A. Srere The infrastructure of the mitochondrial matrix Trends Biochem. Sci., 5 (1980), pp. 120-121 link
Comments P.179 left column bottom paragraph: "The extent of crowding among various types of cells is governed by the presence of numerous biomolecules of varying shapes, sizes and compositions occupying 10–40% of the total cellular volume [ref 18]. For example, an Escherichia coli cell has total concentration of different types of proteins, and various forms of RNA and the DNA chromosome from 300 to 400 g/l [ref 3], the red blood cells contain about 350 g/l of haemoglobin [BNID 107470], human lens contains about 340 g/l of protein [BNID 114207] even as the mitochondrial matrix has the total protein content of about 500 g/l [primary source]."
Entered by Uri M
ID 114208