Estimated number of proteasomes and ribosomes per L929 [murine fibroblast] cell

Range proteasomes 800,000: ribosomes 6,000,000 Table - link
Organism Mouse Mus musculus
Reference Yewdell JW, Reits E, Neefjes J. Making sense of mass destruction: quantitating MHC class I antigen presentation. Nat Rev Immunol. 2003 Dec3(12):952-61. DOI: 10.1038/nri1250 p.958 table 2 & right column bottom paragraphPubMed ID14647477
Primary Source [66] Princiotta, M. F. et al. Quantitating protein synthesis, degradation, and endogenous antigen processing. Immunity 18, 343–354 (2003)PubMed ID12648452
Method Primary source [66] abstract: "Using L929 cells [mouse], [investigators] quantitated the macroeconomics of protein synthesis and degradation and the microeconomics of producing MHC class I associated peptides from viral translation products."
Comments P.958 right column bottom paragraph: "L929 cells were found to have an estimated 6×10^6 ribosomes and 8×10^5 proteasomes." See note beneath table
Entered by Uri M
ID 113783