Lipid composition of the stratum corneum (SC) of epidermis

Range mixture of ceramides 45-50%: cholesterol 25%: free fatty acids 10-15%: each of other lipids <5% % by weight
Organism Unspecified
Reference Madison KC. Barrier function of the skin: "la raison d'être" of the epidermis. J Invest Dermatol. 2003 Aug121(2):231-41. DOI: 10.1046/j.1523-1747.2003.12359.x p.232 left columnPubMed ID12880413
Comments P.231 right column bottom paragraph to p.232 left column: "Thin layer chromatographic analysis of the solvent extractable lipids from SC reveals an unusual lipid composition consisting of a roughly equimolar mixture of ceramides (45–50% by weight), cholesterol (25%), and free fatty acids (10–15%) plus less than 5% each of several other lipids, the most important of which is cholesterol sulfate."
Entered by Uri M
ID 113174