Actin filament turnover in living cells is faster than purified actin turnover in vitro by

Range 10 - 100 fold
Organism Unspecified
Reference McGrath, J.L., Y. Tardy, C.F. Dewey Jr, J.J. Meister, J.H. Hartwig. 1998. Simultaneous measurements of actin filament turnover, filament fraction, and monomer diffusion in endothelial cells. Biophys. J. 75:2070–2078. DOI: 10.1016/S0006-3495(98)77649-0 p.2070 left column bottom paragraphPubMed ID9746549
Primary Source A. Wegner Head to tail polymerization of actin J. Mol. Biol., 108 (1976), pp. 139–150PubMed ID1003481
Comments P.2070 left column bottom paragraph: "Estimates of actin filament turnover in living cells (Theriot and Mitchison, 1991, Theriot and Mitchison, 1992, Wang, 1985 and Finkel et al., 1994) are 10–100 times faster than purified actin in vitro (primary source)."
Entered by Uri M
ID 112784