Rate of transport of hormones in the hypothalamo-neurohypophysial tract

Range 48 - 96 mm/day
Organism Rat Rattus norvegicus
Reference Vahlsing HL, Hirschl RB, Feringa ER. Axoplasmic flow of tritiated proline in the corticospinal tract of the rat. Cell Tissue Res. 1981 214(2):279-87. p.285 bottom paragraphPubMed ID6162568
Primary Source Pickering BT, Jones CW (1971) The biosynthesis and intraneuronal transport of neurohypophysial hormones preliminary studies in the rat. Mem Soc Endocrinol 19: 337-351
Method Abstract:"The rates of axoplasmic transport were studied in the corticospinal tract of the rat by injecting tritiated proline into the sensory-motor cortex and subsequently analyzing the distribution of incorporated label in the spinal cord at intervals after injection. A mathematical model of the anatomy of the corticospinal tract was developed and used in analysis of the data."
Comments P.285 bottom paragraph:"Transport of hormones by the hypothalamo-neurohypophysial tract has been reported as 48-96 mm per day (primary source)."
Entered by Uri M
ID 112230