Force of ATPase motors condensing genetic information into capsid

Range 80 - 100 pN
Organism Virus
Reference Vafabakhsh R et al., Single-molecule packaging initiation in real time by a viral DNA packaging machine from bacteriophage T4. Proc Natl Acad Sci U S A. 2014 Oct 21 111(42):15096-101. doi: 10.1073/pnas.1407235111. p.15096 left column 2nd paragraphPubMed ID25288726
Primary Source Chemla Y, Smith D (2012) Single-molecule studies of viral DNA packaging. Viral Molecular Machines. Advances in Experimental Medicine and Biology, eds Rossmann MG, Rao VB (Springer, New York), Vol 726, pp 549–584 . doi: 10.1007/978-1-4614-0980-9_24.PubMed ID22297530
Comments p.15096 left column 2nd paragraph:"As part of a virus life cycle, genetic information needs to be incorporated into the newly produced virus particles. Tailed bacteriophages, which probably form the largest biomass of the planet (ref 1), and many eukaryotic viruses such as herpes viruses use powerful ATPase motors to achieve this (ref 2). These motors generate forces as high as 80–100 pN and translocate DNA into a preformed prohead until a DNA condensate of near crystalline density fills the interior (primary source)."
Entered by Uri M
ID 111742